Covers current research topics in computational molecular biology. Recent research papers presented from leading conferences such as the International Conference on Computational Molecular Biology (RECOMB) and the Conference on Intelligent Systems for Molecular Biology (ISMB). Topics include original research (both theoretical and experimental) in comparative genomics, sequence and structure analysis, molecular evolution, proteomics, gene expression, transcriptional regulation, biological networks, drug discovery, and privacy. Recent research by course participants also covered. Participants will be expected to present individual projects to the class.